Fondaparinux (Arixtra) is a synthetic anticoagulant based on a pentasaccharide sequence that forms the minimal antithrombin (AT) binding region of heparin. Like low molecular weight heparin, it is an indirect inhibitor of factor Xa, but it does not inhibit thrombin at all. Fondaparinux has a longer half-life than heparin and does not interact with platelets, …