Increase in adoption of in-vitro models, rise in R&D activities in the healthcare sector, surge in drug development activities for novel diseases and technological advancements drive the demand for early toxicity testing across the world. The demand for toxicity testing during the pre-clinical trials has been increased to determine the safety and effectiveness of new drug candidates. Market players have adopted the collaboration strategy to carry out pre-clinical trials and utilizing expertise of each other to carry out testing successfully. The Asia-Pacific region is projected to witness a significant growth, due to adoption of various strategies by market players and and surge in R&D investments in the drug development processes.
Carrying out early toxicity testing at pre-clinical stages in the process of drug development is crucial as toxicity may be the prime reason for drug candidate failure. If the toxicity is determined at the later stages of the drug development process, there may be huge financial losses for developers. Well designed and seamlessly executed pre-clinical trials are essential for drug development programs. The demand for early toxicity testing is expected to surge considerably in the coming years. According to the report published by Allied Market Research, the global early toxicity testing market is expected to reach $1.30 billion by 2025. Following are some of the activities taking place across the world.
Increase in R&D activities in healthcare, surge in stringency of regulatory authorities concerning public healthcare welfare, and rise in adoption of in vitro model and early toxicity testing have boosted the growth of the Europe early toxicity testing market. However, the limitations of preclinical testing hamper the market growth. On the contrary, technological advancements in the field of early toxicity testing are expected to create lucrative opportunities in the near future.
Market players have been adopting the strategy of collaboration to conduct toxicity testing. Affyxell Therapeutics collaborated with Korea Non-Clinical Technology Solution Center (KNTSC) and Biocytogen. This strategy will help in conducting efficient pre-clinical trials. In the drug development stage, pre-clinical trials play a vital role in determining the safety of new drug candidates and the relationship between particular genes and diseases. Through the collaboration, Affyxell Therapeutics aims to carry out toxicity testing of some of its drug candidates with the help of animal and disease models. The company will determine the efficacy of new drug candidates for various diseases.
Among various techniques adopted to carry out early toxicity testing, the in-vitro technique is expected to continue its wide implementation in the next few years. This is due to its cost-effective nature, stringent regulations on animal testing, and advancements in technology. On the other hand, the adoption of the in-silico technique is expected to increase as it provides computer-based testing models that eliminate the need for testing on animals. This technique has a potential to revolutionize the drug development process.
Factors that drive the growth of the market include rise in R&D activities and surge in stringent regulatory authorities concerning public healthcare welfare. Increase in adoption of in vitro model which is the major current early toxicity testing market trend also boosts the growth of the market. However, challenges of preclinical testing hamper the market growth. Furthermore, technological advancements in preclinical diagnostic equipment provide lucrative opportunities for the early toxicity testing market growth.
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The report includes in-depth analysis of the major market players such as General Electric Company (GE Healthcare), Agilent Technologies, Inc., Evotec AG (Cyprotex), Danaher Corporation (Beckman Coulter, Inc.), Bruker Corporation, Bioanalytical Systems, Inc., PerkinElmer Inc., Thermo Fisher Scientific, Inc., The Jackson Laboratory, and Enzo Biochem, Inc. (Enzo Clinical Labs, Inc.).
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