According to AMRโs prediction, Acute ischemic stroke is a medical emergency that occurs when the blood supply to part of the brain is disrupted, causing brain cells to die. The most common cause of ischemic stroke is a blood clot that forms in an artery supplying blood to the brain. Moreover, stroke leads to 1 out of every 20 deaths, costing around $34 billion to U.S. annually. Higher rates of mortality associated with strokes highlight an impending need for innovative drugs and diagnostic devices.
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Diagnosis: The diagnosis of acute ischemic stroke is typically made by a combination of clinical assessment, medical imaging, and laboratory tests. The clinical assessment involves evaluating the patient’s symptoms and medical history, including risk factors for stroke such as high blood pressure, diabetes, and smoking. Imaging tests, such as a computed tomography (CT) scan or magnetic resonance imaging (MRI), can help confirm the diagnosis and determine the location and extent of the stroke. Laboratory tests, such as a blood test to measure the patient’s clotting ability, may also be performed to guide treatment.
Treatment: The treatment of acute ischemic stroke depends on the severity and location of the stroke, as well as the patient’s overall health and medical history. The goal of treatment is to restore blood flow to the affected part of the brain as quickly as possible to prevent further damage and improve outcomes.
- Thrombolytic therapy: Thrombolytic therapy involves the use of drugs that dissolve blood clots, such as alteplase. This treatment is most effective when administered within the first few hours after the onset of symptoms, and may not be appropriate for all patients.
- Endovascular treatment: Endovascular treatment involves the use of catheters and other devices to remove or dissolve the blood clot. This treatment may be recommended for patients who are not eligible for thrombolytic therapy, or for those with large or inaccessible blood clots.
- Antiplatelet and anticoagulant therapy: These medications help prevent the formation of blood clots and may be prescribed to prevent future strokes.
- Rehabilitation: After the acute phase of treatment, rehabilitation may be necessary to help patients recover from the effects of the stroke. This may involve physical therapy, speech therapy, and occupational therapy.
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Prompt recognition and treatment of acute ischemic stroke are critical for improving outcomes and reducing the risk of long-term disability or death. Patients who experience symptoms of stroke, such as sudden weakness or numbness on one side of the body, difficulty speaking or understanding speech, or sudden vision changes, should seek emergency medical attention immediately.
Key Market Players –
Major key players that operate in the industry are Abbott Laboratories,, Medtronic plc,, Boston Scientific Corporation, Cordis Corporation,, Koninklijke Philips N.V., GE Healthcare, , Siemens AG,, Stryker Corporation,, Genentech, Inc., Merck & Co., Inc.
By Region –
North America (U.S., Canada, Mexico)
Europe (Germany, France, U.K., Italy, Spain, Rest of Europe)
LAMEA (Brazil, Saudi Arabia, South Africa, Rest of LAMEA)
Asia-Pacific (Japan, China, Australia, India, South Korea, Rest of Asia-Pacific)
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