Scaffolds mimic the extracellular matrix of the native tissue, recapitulating the in vivo milieu and allowing cells to influence their own microenvironments. They usually serve purposes such as allow cell attachment and migration, deliver & retain cells and biochemical factors, and exert certain mechanical & biological influences to modify the behavior of the cell phase. In addition, scaffold can act as a delivery vehicle for exogenous cells and matrix for cell adhesion to facilitate certain unit cell processes (for example, mitosis, synthesis, migration) of cells in vivo or for cells seeded in vitro. It also serves as a barrier to prevent the infiltration of surrounding tissue that may impede the process of regeneration. Scaffold technology technique is gaining popularity in the healthcare research sector, owing to increased demand for body reconstruction procedures and tissue engineering.
The global scaffold technology market size was valued at $398.91 million in 2019, and is projected to reach $1,257.17 million by 2027, registering a CAGR of 16.9% from 2020 to 2027.
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Advantages of 3D culture techniques over 2D methods, increase in use of 3D cell cultures for cancer research, surge in demand for organ transplantation, and increase in investment for R&D activities have driven the growth of the global scaffold technology market. On the other hand, high implementation costs and irregularity in 3D cell culture outcomes impede the growth to some extent. However, technological advancements are anticipated to pave the way for lucrative opportunities in the industry.
Based on product type, the scaffold technology market is divided into natural scaffold and synthetic scaffold. On the basis of type, the market is fragmented into macro-porous scaffolds, micro-porous scaffolds, nano-porous scaffolds, and solid scaffolds. By end user, the market is segregated into biotechnology & pharmaceutical companies, contract research laboratories, and academic institutes.
Key Findings of the Scaffold Technology Market
- By type, the micro-porous scaffolds segment occupied the largest market share in the global scaffold technology market in 2019.
- By application, the regenerative medicine segment is anticipated to grow with the highest CAGR during the forecast period.
- By end user, the academic institutes segment held the largest market share in 2019, and is anticipated to maintain its dominance during the forecast period.
- The U.S. contributed the highest revenue in 2019 in the market.
- By region, Asia-Pacific is anticipated to experience 18.7% CAGR during the forecast period.
By region, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA. Based on application, the market is divided into cancer research, stem cell research, drug discovery, regenerative medicine, and others. The cancer research segment dominated the global scaffold technology market in 2019, and is anticipated to maintain its dominance during forecast period. This is attributed to rise in prevalence of cancer, which has led to development of newer therapies for the prevention and treatment of cancer.
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North America accounted for the largest scaffold technology market share in 2019, and is anticipated to maintain its dominance from 2019 to 2027 due to high expenditure on R&D, presence of major players & their product availability, and well-established healthcare infrastructure in the region. However, Asia-Pacific is expected to register the highest CAGR during the forecast period as governments of Asian countries are investing in the development of healthcare infrastructure.
Leading players of the global Scaffold Technology market analyzed in the research include Advanced Biomatrix, Inc., Agilent Technologies, Inc. (Biotek), Merck KGaA (Sigmaaldrich), BioVison, Incorporated, Thermo Fisher Scientific Inc, 3D Biotek LLC, PromoCell GmbH, Reprocell, Corning Incorporated, Incorporation.
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