Proteins are extensively used in applied and basic biomedical research. However, they are only marginally stable and can be expressed within certain limits which affects its applications and the research. Protein stability is the net balance of forces, which determine whether a protein will be its native folded conformation or a denatured (unfolded or extended) state. Protein stability is an important topic of interest for majority of biotechnology, pharmaceutical, food and adjacent industries. An understanding of protein stability is essential for optimizing the formulation, storage, expression, purification and structure of proteins along with its effective application in the industry. Processes ranging right from large-scale industrial protein production and high throughput screening to the more specific pharmaceutical protein-drug, protein -protein interactions and protein crystallization can be impacted.
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The importance of protein stability is widely recognized where high stability is of prioritized in pharmaceutical and biotechnological applications where proteins must carry out its function for long period of time in unfavorable conditions such as increased temperatures and broad pH environment, or in the presence of organic solvents. Protein stability also helps with drug release in the human body, which is crucial for effectiveness and accurate interaction of drug and body as well as reducing potentially harmful effects.
COVID-19 scenario analysis:
- Due to the COVID – 19 outbreak, majority of healthcare, pharmaceutical and biotechnology organizations have concentrated on diagnostics kits, safety wearables (PPE kits, face shields, masks) and treatment therapies and medication against Novel coronavirus
- R&D labs are also focusing on finding a breakthrough vaccine against Novel coronavirus where protein studies are in focus
- Peptide KRSFIEDLLFNKV occurs in the spike glycoprotein and is responsible for the binding of SARS coronaviruses to lung cells and its activation of the spike protein by proteolytic cleavage
- This understanding related to the peptide KRSFIEDLLFNKV and spike protein plays anchoring role in learning about the nature of this disease and such data is of utmost importance and conserved and researched to get useful insights during the study of coronaviruses
Top impacting factors: Market Scenario Analysis, Trends, Drivers and Impact Analysis:
Proteins are the building blocks of an organism and Protein stability is crucial as it determines the functionality and active state of the proteins. There are several approaches and techniques to determine the protein stability. It can be determined through chromatography, Spectroscopy, Surface Plasma Resonance (SPR), High-Performance Liquid Chromatography (HPLC), Differential Scanning Calorimeter (DSC). Protein stability analysis is carried out by pharmaceutical & biotechnological organizations for new drug development and research. The rising number of pharmaceutical and biotech organizations in the global Protein Stability analysis Market, especially in the developing economies, increasing spend on healthcare, importance of Protein stability in protein studies related to diseases, in current scenario Novel coronaviruses, the development of new high-throughput techniques and increasing number of Contract Research Organizations (CRO) and Contract Research Manufacturing Organizations (CRMO) are the drivers fueling the growth in the Protein Stability analysis Market. However, the amount of monetary spending and time that goes into these studies and the impact on pharmaceutical and biotech organizations due to ongoing COVID-19 pandemic are the restricting factors for Protein Stability market.
Key benefits of the report:
- This study presents the analytical depiction of the global protein stability analysis industry along with the current trends and future estimations to determine the imminent investment pockets.
- The report presents information related to key drivers, restraints, and opportunities along with detailed analysis of the global Protein Stability analysis Market share.
- The current market is quantitatively analysed from 2020 to 2027 to highlight the global protein stability analysis market growth scenario.
- Porter’s five forces analysis illustrates the potency of buyers & suppliers in the Protein Stability analysis Market.
- The report provides a detailed global Protein Stability analysis Market analysis based on competitive intensity and how the competition will take shape in coming years.
Key Market Players
- Agilent Technologies, Inc.
- GE Healthcare
- Enzo Biochem Inc.
- Thermo Fisher Scientific Inc.
- PerkinElmer Inc.
- NanoTemper
- Malvern Panalytical Ltd.
- HORIBA, Ltd.
- Unchained Labs
- SETARAM Instrumentation.
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